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"If one is using rimonabant, patients should be monitored carefully for the emergence of depressive symptoms and/or suicidal thoughts," he added. 25 percent increase in percent atheroma volume (PAV) in those taking rimonabant, compared to 0. Food and Drug Administration finding of increased risk of suicide during treatment with rimonabant, we recommend increased alertness by physicians to these potentially severe psychiatric adverse reactions. Effect of Rimonabant on Body Weight and the Metabolic Syndrome in Overweight Patients. Effects of the cannabinoid-1 receptor blocker rimonabant on weight reduction and cardiovascular risk factors in overweight patients: 1-year experience from the RIO-Europe study. A CB1 antagonist called rimonabant is currently marketed overseas for weight loss.
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